• Ohio’s Third Frontier program announced a $46 million investment in 100 small companies, helping establish Northeast Ohio as a high-tech and health innovation hub.  
  • Louisville, KY-based Appriss Health, a leader in cloud-based care coordination software and analytics solutions focused on behavioral health and substance use disorders, has acquired PatientPing.

  • With some strategic assistance from Innovation Works, Pittsburgh’s main nonprofit, early-stage investor for startups, $372 million was invested in Pittsburgh tech startups this year
  • St. Louis VC firm RiverVest Venture Partners closed on of its RiverVest Venture Fund V, with $275 million of capital commitments to continue investing in high-impact biopharma and medical device innovation.
  • Demonstrating the role that higher education and the state can play in building tech-based economic development in rural communities, Ohio University-supported Stirling Ultracold has been acquired by publicly traded BioLife Solutions.